Monday, June 24

Research helps gene-directed administration of BRCA1 and BRCA2 gene carrie…



Findings of large-scale study on 572 Asian families supports gene-directed management of BRCA1 and BRCA2 gene carriers in Singapore
Credit: National Cancer Centre Singapore

A team of clinician-scientists have conducted the largest study done to date of BRCA1 and BRCA2 (BReast CAncer Gene 1 and 2) carriers in an Asian population and refined breast and ovarian cancer risk estimates for this population. The findings, published in The Lancet Regional Health—Western Pacific, will better guide the clinical management of Asian patients with BRCA1 and BRCA2 mutations.

Breast cancer is the most common and top cause of cancer mortality for females in Singapore, while ovarian cancer ranks 6th in incidence and mortality for the…


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